9UE8

Crystal structure of MPXV A35R in complex with a neutralizing antibody BA345

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, I, M, Q... (A, E, I, M, Q...)	345 Heavy Chain	polymer	221	23186.0	6		Homo sapiens
2	B, F, J, N, R... (B, F, J, N, R...)	345 Light Chain	polymer	215	23445.0	6		Homo sapiens
3	C, D, G, H, K... (C, D, G, H, K...)	Protein OPG161	polymer	152	16962.4	12	UniProt (A0A7H0DND2) Pfam (PF05966)	Monkeypox virus

Sequence modifications

C, D, G, H, K, L, O, P, S, T, W, X: -39 - 84 (UniProt: A0A7H0DND2)

PDB	External Database	Details
Gly 85	-	expression tag
Ser 86	-	expression tag
Gly 87	-	expression tag
Leu 88	-	expression tag
Asn 89	-	expression tag
Asp 90	-	expression tag
Ile 91	-	expression tag
Phe 92	-	expression tag
Glu 93	-	expression tag
Ala 94	-	expression tag
Gln 95	-	expression tag
Lys 96	-	expression tag
Ile 97	-	expression tag
Glu 98	-	expression tag
Trp 99	-	expression tag
His 100	-	expression tag
Glu 101	-	expression tag
Ala 102	-	expression tag
Ala 103	-	expression tag
Ala 104	-	expression tag
His 105	-	expression tag
His 106	-	expression tag
His 107	-	expression tag
His 108	-	expression tag
His 109	-	expression tag
His 110	-	expression tag
His 111	-	expression tag
His 112	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	483335.3
All*	Total formula weight	483335.3

*Water molecules are not included.