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9UCX

Cryo-EM structure of R2Tg bound to template RNA and target DNA in the target-primed reverse transcription initiation state (state 1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Reverse transcriptase-like proteinpolymer1287146346.71Taeniopygia guttata
2B
(B)
R2Tg 3'UTR RNApolymer11737589.31Taeniopygia guttata
3C
(C)
28S DNA top strandpolymer8024766.91GenBank (2946502449)Taeniopygia guttata
4D
(D)
28S DNA bottom strand, 3' sidepolymer5015263.81Taeniopygia guttata
5E
(E)
28S DNA bottom strand, 5' side (priming strand)polymer319550.21Taeniopygia guttata
6F, G, H, I
(A)
ZINC IONnon-polymer65.44Chemie (ZN)
PubChem (32051)
7J, K
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
PubChem (888)
8L
(A)
THYMIDINE-5'-TRIPHOSPHATEnon-polymer482.21Chemie (TTP)
9M, N, O, P, Q
(A, B, C, D, E)
waterwater18.0353Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight233516.9
Non-Polymers*Number of molecules7
Total formula weight792.4
All*Total formula weight234309.3
*Water molecules are not included.

260896

PDB entries from 2026-10-14

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