9UBR

CryoEM structure of human Galectin-10 with iTrimbody

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	PrAC-5350A,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase	polymer	260	28139.7	6	UniProt (Q9WXS1)	synthetic construct
2	G, H, I, J, K... (G, H, I, J, K...)	hGal10-nanobody	polymer	118	12480.7	6		synthetic construct
3	M, N, O, P, Q... (M, N, O, P, Q...)	Galectin-10	polymer	140	16183.4	6	UniProt (Q05315)	Homo sapiens (human)	Gal-10,Charcot-Leyden crystal protein,CLC,Eosinophil lysophospholipase,Lysolecithin acylhydrolase

Sequence modifications

A, B, C, D, E, F: 8 - 63 (PDB: 9UBR)
A, B, C, D, E, F: 64 - 267 (UniProt: Q9WXS1)

PDB	External Database	Details
Ile 87	Lys 25	conflict
Val 91	Leu 29	conflict
Ala 95	Glu 33	conflict
Ala 116	Glu 54	conflict
Val 119	Phe 57	conflict

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	340822.8
All*	Total formula weight	340822.8

*Water molecules are not included.