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9UAP

cryo-EM structure of ligand-free active-state M1 muscarinic acetylcholine receptor with alpha5 helix of G11 protein complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
M1 muscarinic acetylcholine receptor, de novo design proteinpolymer37242070.71Homo sapiens (human)
2B
(B)
Guanine nucleotide-binding protein subunit alpha-11polymer273152.71UniProt (P29992)Homo sapiens (human)G alpha-11,G-protein subunit alpha-11,Guanine nucleotide-binding protein G(y) subunit alpha
Sequence modifications
B: 333 - 359 (UniProt: P29992)
PDBExternal DatabaseDetails
Pro 334-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight45223.4
All*Total formula weight45223.4
*Water molecules are not included.

245011

PDB entries from 2025-11-19

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