9U7R
Substrate-free human 26S proteasome purified by midnolin, 20S proteasome, RPTs and RPN11 part
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (c) | 26S proteasome non-ATPase regulatory subunit 14 | polymer | 309 | 34488.8 | 1 | UniProt (O00487) | Homo sapiens (human) | 26S proteasome regulatory subunit RPN11,26S proteasome-associated PAD1 homolog 1 |
| 2 | B (A) | 26S proteasome regulatory subunit 7 | polymer | 433 | 48700.8 | 1 | UniProt (P35998) | Homo sapiens (human) | 26S proteasome AAA-ATPase subunit RPT1,Proteasome 26S subunit ATPase 2 |
| 3 | C (B) | 26S proteasome regulatory subunit 4 | polymer | 440 | 49260.5 | 1 | UniProt (P62191) | Homo sapiens (human) | P26s4,26S proteasome AAA-ATPase subunit RPT2,Proteasome 26S subunit ATPase 1 |
| 4 | D (C) | 26S proteasome regulatory subunit 8 | polymer | 398 | 44852.1 | 1 | UniProt (P62195) | Homo sapiens (human) | 26S proteasome AAA-ATPase subunit RPT6,Proteasome 26S subunit ATPase 5,Proteasome subunit p45,Thyroid hormone receptor-interacting protein 1,TRIP1,p45/SUG |
| 5 | E (D) | 26S proteasome regulatory subunit 6B | polymer | 418 | 47426.1 | 1 | UniProt (P43686) | Homo sapiens (human) | 26S proteasome AAA-ATPase subunit RPT3,MB67-interacting protein,MIP224,Proteasome 26S subunit ATPase 4,Tat-binding protein 7,TBP-7 |
| 6 | F (E) | Proteasome 26S subunit, ATPase 6 | polymer | 403 | 45867.0 | 1 | UniProt (A0A087X2I1) | Homo sapiens (human) | 26S proteasome regulatory subunit 10B |
| 7 | G (F) | 26S proteasome regulatory subunit 6A | polymer | 439 | 49266.5 | 1 | UniProt (P17980) | Homo sapiens (human) | 26S proteasome AAA-ATPase subunit RPT5,Proteasome 26S subunit ATPase 3,Proteasome subunit P50,Tat-binding protein 1,TBP-1 |
| 8 | H, V (G, g) | Proteasome subunit alpha type-6 | polymer | 245 | 27301.3 | 2 | UniProt (P60900) | Homo sapiens (human) | 27 kDa prosomal protein,PROS-27,p27K,Macropain iota chain,Multicatalytic endopeptidase complex iota chain,Proteasome iota chain,Proteasome subunit alpha-1,alpha-1 |
| 9 | I, W (H, h) | Proteasome subunit alpha type-2 | polymer | 233 | 25796.3 | 2 | UniProt (P25787) | Homo sapiens (human) | Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3,Proteasome subunit alpha-2,alpha-2 |
| 10 | J, X (I, i) | Proteasome subunit alpha type-4 | polymer | 260 | 29394.6 | 2 | UniProt (P25789) | Homo sapiens (human) | Macropain subunit C9,Multicatalytic endopeptidase complex subunit C9,Proteasome component C9,Proteasome subunit L,Proteasome subunit alpha-3,alpha-3 |
| 11 | K, Y (J, j) | Proteasome subunit alpha type-7 | polymer | 247 | 27798.7 | 2 | UniProt (O14818) | Homo sapiens (human) | Proteasome subunit RC6-1,Proteasome subunit XAPC7,Proteasome subunit alpha-4,alpha-4 |
| 12 | L, Z (K, k) | Proteasome subunit alpha type-5 | polymer | 240 | 26304.8 | 2 | UniProt (P28066) | Homo sapiens (human) | Macropain zeta chain,Multicatalytic endopeptidase complex zeta chain,Proteasome subunit alpha-5,alpha-5,Proteasome zeta chain |
| 13 | AA, M (L, l) | Isoform Long of Proteasome subunit alpha type-1 | polymer | 268 | 30150.3 | 2 | UniProt (P25786) | Homo sapiens (human) | 30 kDa prosomal protein,PROS-30,Macropain subunit C2,Multicatalytic endopeptidase complex subunit C2,Proteasome component C2,Proteasome nu chain,Proteasome subunit alpha-6,alpha-6 |
| 14 | BA, N (M, m) | Proteasome subunit alpha type-3 | polymer | 254 | 28338.1 | 2 | UniProt (P25788) | Homo sapiens (human) | Macropain subunit C8,Multicatalytic endopeptidase complex subunit C8,Proteasome component C8,Proteasome subunit alpha-7,alpha-7 |
| 15 | CA, O (N, n) | Proteasome subunit beta type-6 | polymer | 238 | 25246.5 | 2 | UniProt (P28072) | Homo sapiens (human) | Macropain delta chain,Multicatalytic endopeptidase complex delta chain,Proteasome delta chain,Proteasome subunit Y,Proteasome subunit beta-1,beta-1 |
| 16 | DA, P (O, o) | Proteasome subunit beta type-7 | polymer | 276 | 29869.2 | 2 | UniProt (Q99436) | Homo sapiens (human) | Macropain chain Z,Multicatalytic endopeptidase complex chain Z,Proteasome subunit Z,Proteasome subunit beta-2,beta-2 |
| 17 | EA, Q (P, p) | Proteasome subunit beta type-3 | polymer | 204 | 22841.7 | 2 | UniProt (P49720) | Homo sapiens (human) | Proteasome chain 13,Proteasome component C10-II,Proteasome subunit beta-3,beta-3,Proteasome theta chain |
| 18 | FA, R (Q, q) | Proteasome subunit beta type-2 | polymer | 201 | 22864.3 | 2 | UniProt (P49721) | Homo sapiens (human) | Macropain subunit C7-I,Multicatalytic endopeptidase complex subunit C7-I,Proteasome component C7-I,Proteasome subunit beta-4,beta-4 |
| 19 | GA, S (R, r) | Proteasome subunit beta type-5 | polymer | 262 | 28379.1 | 2 | UniProt (P28074) | Homo sapiens (human) | Macropain epsilon chain,Multicatalytic endopeptidase complex epsilon chain,Proteasome chain 6,Proteasome epsilon chain,Proteasome subunit MB1,Proteasome subunit X,Proteasome subunit beta-5,beta-5 |
| 20 | HA, T (S, s) | Proteasome subunit beta type-1 | polymer | 240 | 26391.2 | 2 | UniProt (P20618) | Homo sapiens (human) | Macropain subunit C5,Multicatalytic endopeptidase complex subunit C5,Proteasome component C5,Proteasome gamma chain,Proteasome subunit beta-6,beta-6 |
| 21 | IA, U (T, t) | Proteasome subunit beta type-4 | polymer | 263 | 29100.0 | 2 | UniProt (P28070) | Homo sapiens (human) | 26 kDa prosomal protein,HsBPROS26,PROS-26,Macropain beta chain,Multicatalytic endopeptidase complex beta chain,Proteasome beta chain,Proteasome chain 3,HsN3,Proteasome subunit beta-7,beta-7 |
| 22 | JA (c) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 23 | KA, MA, PA, QA (A, B, D, E) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 24 | LA, NA, RA, TA (A, B, E, F) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 25 | OA, SA (C, F) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 26 | UA, VA, WA, XA, YA... (N, O, R, n, o...) | N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide | non-polymer | 475.6 | 6 | BIRD (PRD_000907) Chemie (LDZ) PubChem (21118289) PubChem (42636703) PubChem (44119981) PubChem (44367242) PubChem (45103781) PubChem (45103890) PubChem (45104082) PubChem (45104083) PubChem (462382) PubChem (45103889) PubChem (58864900) PubChem (60008819) PubChem (87400659) PubChem (88909681) PubChem (89084460) PubChem (107707) PubChem (6914692) PubChem (92851396) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 35 |
| Total formula weight | 1079413.8 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 5899.5 | |
| All* | Total formula weight | 1085313.3 |
