9U55

Cryo-EM structure of human OAT1 in complex with probenecid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Isoform 2 of Solute carrier family 22 member 6	polymer	572	63119.2	1	UniProt (Q4U2R8) Pfam (PF00083)	Homo sapiens (human)	Organic anion transporter 1,hOAT1,PAH transporter,hPAHT,Renal organic anion transporter 1,hROAT1
2	B (A)	4-(dipropylsulfamoyl)benzoic acid	non-polymer		285.4	1	Chemie (RTO)

Sequence modifications

A: 1 - 550 (UniProt: Q4U2R8)

PDB	External Database	Details
His 551	-	expression tag
His 552	-	expression tag
His 553	-	expression tag
His 554	-	expression tag
His 555	-	expression tag
His 556	-	expression tag
His 557	-	expression tag
His 558	-	expression tag
His 559	-	expression tag
His 560	-	expression tag
Gly 561	-	expression tag
Ser 562	-	expression tag
Val 563	-	expression tag
Glu 564	-	expression tag
Asp 565	-	expression tag
Tyr 566	-	expression tag
Lys 567	-	expression tag
Asp 568	-	expression tag
Asp 569	-	expression tag
Asp 570	-	expression tag
Asp 571	-	expression tag
Lys 572	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63119.2
Non-Polymers*	Number of molecules	1
	Total formula weight	285.4
All*	Total formula weight	63404.5

*Water molecules are not included.