9U4S

Crystal Structure of PI5P4K-gamma in complex with n40

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	polymer	349	40205.9	2	UniProt (Q8TBX8) Pfam (PF01504)	Homo sapiens (human)	Phosphatidylinositol 5-phosphate 4-kinase type II gamma,PI(5)P 4-kinase type II gamma,PIP4KII-gamma
2	C, D (A, B)	~{N}-[5-(4-oxidanylidene-3-propyl-quinazolin-6-yl)pyridin-2-yl]pentanamide	non-polymer		364.4	2	Chemie (A1EN5)
3	E, F (A, B)	water	water		18.0	51	Chemie (HOH)

Sequence modifications

A, B: 32 - 421 (UniProt: Q8TBX8)

PDB	External Database	Details
Gly 31	-	expression tag
-	Ala 300	deletion
-	Pro 301	deletion
-	Val 302	deletion
-	Arg 303	deletion
-	Glu 304	deletion
-	Asp 305	deletion
-	Glu 306	deletion
-	Ser 307	deletion
-	Glu 308	deletion
-	Val 309	deletion
-	Asp 310	deletion
-	Gly 311	deletion
-	Asp 312	deletion
-	Cys 313	deletion
-	Ser 314	deletion
-	Leu 315	deletion
-	Thr 316	deletion
-	Gly 317	deletion
-	Pro 318	deletion
-	Pro 319	deletion
-	Ala 320	deletion
-	Leu 321	deletion
-	Val 322	deletion
-	Gly 323	deletion
-	Ser 324	deletion
-	Tyr 325	deletion
-	Gly 326	deletion
-	Thr 327	deletion
-	Ser 328	deletion
-	Pro 329	deletion
-	Glu 330	deletion
-	Gly 331	deletion
-	Ile 332	deletion
-	Gly 333	deletion
-	Gly 334	deletion
-	Tyr 335	deletion
-	Ile 336	deletion
-	His 337	deletion
-	Ser 338	deletion
-	His 339	deletion
-	Arg 340	deletion
-	Pro 341	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80411.9
Non-Polymers*	Number of molecules	2
	Total formula weight	728.9
All*	Total formula weight	81140.8

*Water molecules are not included.