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9U19

Crystal structure of the NKX2.1 homeodomain in complex with a 12-bp DNA duplex containing a CACG motif variant

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, D)
CACG-containing 12bp forward strandpolymer123653.42Homo sapiens
2B, E
(B, E)
12bp reverse complementarypolymer123671.42Homo sapiens
3C, F
(C, F)
Homeobox protein Nkx-2.1polymer597489.82UniProt (P43699)Homo sapiens (human)Homeobox protein NK-2 homolog A,Thyroid nuclear factor 1,Thyroid transcription factor 1,TTF-1,Thyroid-specific enhancer-binding protein,T/EBP
4G
(C)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5H, I, J, K, L...
(A, B, C, D, E...)
waterwater18.0251Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight29629.2
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight29653.5
*Water molecules are not included.

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PDB entries from 2026-03-18

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