9U06

6B5 (Fab) - Polio 3 (VLP) complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Capsid proteins, VP1	polymer	300	33562.8	1	UniProt (Q84895)	Poliovirus 3
2	B (B)	Capsid proteins, VP0	polymer	340	37623.0	1	UniProt (Q84895)	Poliovirus 3
3	C (C)	Capsid proteins, VP3	polymer	238	26315.1	1	UniProt (Q84895)	Poliovirus 3
4	D (H)	6B5 Fab Heavy chain	polymer	478	52752.3	1		Homo sapiens
5	E (L)	6B5 Fab Light chain	polymer	235	24929.6	1		Homo sapiens
6	F (A)	SPHINGOSINE	non-polymer		299.5	1	Chemie (SPH) PubChem (5326412)
7	G, H, I, J, K (A, B, C, H, L)	water	water		18.0	434	Chemie (HOH)

Sequence modifications

A: 1 - 300 (UniProt: Q84895)

PDB	External Database	Details
Met 105	Thr 683	engineered mutation
Leu 132	Phe 710	engineered mutation

B: 1 - 340 (UniProt: Q84895)

PDB	External Database	Details
Ala 67	Unk 67	engineered mutation
Ile 87	Leu 87	engineered mutation
Met 284	Leu 284	engineered mutation
Glu 310	Asp 310	engineered mutation

C: 1 - 238 (UniProt: Q84895)

PDB	External Database	Details
Tyr 19	His 359	engineered mutation
Phe 85	Leu 425	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	175182.9
Non-Polymers*	Number of molecules	1
	Total formula weight	299.5
All*	Total formula weight	175482.4

*Water molecules are not included.