9U04

LX-2D6 (Fab) - Polio 1 (VLP) complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Capsid protein VP1	polymer	302	33447.6	1	UniProt (P03300) Pfam (PF00073)	Human poliovirus 1 Mahoney	P1D,Virion protein 1
2	B (B)	Capsid protein VP0	polymer	340	37334.6	1	UniProt (P03300) Pfam (PF02226) Pfam (PF00073)	Human poliovirus 1 Mahoney	VP4-VP2
3	C (C)	Capsid protein VP3	polymer	238	26550.5	1	UniProt (P03300) Pfam (PF00073)	Human poliovirus 1 Mahoney	P1C,Virion protein 3
4	D (H)	LX-2D6 Fab Heavy chain	polymer	468	50983.5	1		Homo sapiens
5	E (L)	LX-2D6 Fab Light chain	polymer	235	24864.7	1		Homo sapiens
6	F (A)	PALMITIC ACID	non-polymer		256.4	1	Chemie (PLM) PubChem (985)
7	G (B)	MYRISTIC ACID	non-polymer		228.4	1	Chemie (MYR) PubChem (11005)
8	H, I, J, K, L (A, B, C, H, L)	water	water		18.0	434	Chemie (HOH)

Sequence modifications

A: 1 - 302 (UniProt: P03300)

PDB	External Database	Details
Pro 248	His 827	engineered mutation

B: 2 - 341 (UniProt: P03300)

PDB	External Database	Details
Gly 18	Arg 18	engineered mutation
Ala 94	Thr 94	engineered mutation
Glu 126	Asp 126	engineered mutation

C: 1 - 238 (UniProt: P03300)

PDB	External Database	Details
Met 119	Leu 460	engineered mutation
Ser 123	Phe 464	variant
Leu 178	Gln 519	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	173181.0
Non-Polymers*	Number of molecules	2
	Total formula weight	484.8
All*	Total formula weight	173665.8

*Water molecules are not included.