9TZY

SARM1 TIR with BEXi adduct 17

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, C, D, B)	NAD(+) hydrolase SARM1	polymer	142	16148.5	4	UniProt (Q6SZW1)	Homo sapiens (human)	NADase SARM1,hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,MyD88-5,SAM domain-containing protein 2,Tir-1 homolog,HsTIR
2	E, F, G, H (A, C, D, B)	[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-[3-[(1~{S})-1-[4-[[2,2-bis(fluoranyl)-2-[(3~{R})-oxolan-3-yl]ethanoyl]amino]phenyl]ethyl]-2-methyl-imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate	non-polymer		891.7	4	Chemie (A1JZ0)

Sequence modifications

A, C, D, B: 560 - 700 (UniProt: Q6SZW1)

PDB	External Database	Details
Ser 559	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	64594.1
Non-Polymers*	Number of molecules	4
	Total formula weight	3566.7
All*	Total formula weight	68160.8

*Water molecules are not included.