9TZ2

human formylglycine-generating enzyme FGE, with surface loop and active site Cu(I)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Formylglycine-generating enzyme	polymer	323	36128.9	1	UniProt (Q8NBK3)	Homo sapiens (human)	FGE,C-alpha-formylglycine-generating enzyme 1,Sulfatase-modifying factor 1
2	B (B)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3	C (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL) PubChem (753)
4	D (A)	OXYGEN MOLECULE	non-polymer		32.0	1	Chemie (OXY) PubChem (977)
5	E, F (A)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA) PubChem (271)
6	G (A)	COPPER (I) ION	non-polymer		63.5	1	Chemie (CU1) PubChem (104815)
7	H, I, J, K (A)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL) PubChem (312)
8	L (A)	water	water		18.0	405	Chemie (HOH)

Sequence modifications

A: 73 - 374 (UniProt: Q8NBK3)

PDB	External Database	Details
Ala 64	-	expression tag
Asp 65	-	expression tag
Leu 66	-	expression tag
Gly 67	-	expression tag
Ser 68	-	expression tag
Ser 69	-	expression tag
Met 70	-	expression tag
Glu 71	-	expression tag
Phe 72	-	expression tag
Ser 375	-	expression tag
Gly 376	-	expression tag
Arg 377	-	expression tag
Gly 378	-	expression tag
Ser 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag
His 385	-	expression tag
His 386	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36128.9
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	9
	Total formula weight	409.6
All*	Total formula weight	36962.9

*Water molecules are not included.