9TXK
Cryo-EM structure of active ITIH4N with 12A12 F(ab)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 3 of Inter-alpha-trypsin inhibitor heavy chain H4 | polymer | 630 | 70018.9 | 1 | UniProt (Q14624) Pfam (PF08487) Pfam (PF00092) | Homo sapiens (human) | ITI heavy chain H4,ITI-HC4,Inter-alpha-inhibitor heavy chain 4,Inter-alpha-trypsin inhibitor family heavy chain-related protein,IHRP,Plasma kallikrein sensitive glycoprotein 120,Gp120,PK-120 |
| 2 | B (D) | 12A12 mAb F(ab) heavy chain | polymer | 227 | 24204.1 | 1 | Mus musculus | ||
| 3 | C (E) | 12A12 mAb F(ab) light chain | polymer | 213 | 23693.2 | 1 | Mus musculus | ||
| 4 | D (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E, F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) PubChem (24139) | |||
| 6 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 7 | H (A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 117916.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 466.7 | |
| All* | Total formula weight | 118807.3 |
