9TXJ
Cryo-EM structure of native ITIH4 with 12A12 F(ab)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 3 of Inter-alpha-trypsin inhibitor heavy chain H4 | polymer | 906 | 100793.1 | 1 | UniProt (Q14624) Pfam (PF08487) Pfam (PF00092) Pfam (PF06668) | Homo sapiens (human) | ITI heavy chain H4,ITI-HC4,Inter-alpha-inhibitor heavy chain 4,Inter-alpha-trypsin inhibitor family heavy chain-related protein,IHRP,Plasma kallikrein sensitive glycoprotein 120,Gp120,PK-120 |
| 2 | B (D) | 12A12 mAb F(ab) heavy chain | polymer | 227 | 24204.1 | 1 | Mus musculus | ||
| 3 | C (E) | 12A12 mAb F(ab) light chain | polymer | 213 | 23693.2 | 1 | Mus musculus | ||
| 4 | D, E, F, G (B, C, F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) |
Sequence modifications
A: 1 - 900 (UniProt: Q14624)
| PDB | External Database | Details |
|---|---|---|
| His 901 | - | expression tag |
| His 902 | - | expression tag |
| His 903 | - | expression tag |
| His 904 | - | expression tag |
| His 905 | - | expression tag |
| His 906 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 148690.4 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| All* | Total formula weight | 150388.0 |
