9TW7

FgFR4-D2 in complex with Fab5322

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Fibroblast growth factor receptor 4	polymer	114	13229.0	2	UniProt (P22455) Pfam (PF07679)	Homo sapiens (human)	FGFR-4
2	C, D (H, I)	Fab5322 Heavy Chain	polymer	223	24335.3	2		Mus musculus
3	E, F (L, M)	Fab5322 Light Chain	polymer	212	23273.8	2		Mus musculus
4	G, I (A, B)	Xylitol	non-polymer		152.1	2	Chemie (XYL)
5	H (A)	ETHANOL	non-polymer		46.1	1	Chemie (EOH)
6	J, K (I)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4) PubChem (1061)
7	L, M, N, O, P... (A, B, H, I, L...)	water	water		18.0	142	Chemie (HOH)

Sequence modifications

A, B: 2 - 106 (UniProt: P22455)

PDB	External Database	Details
Met 1	-	initiating methionine
Leu 107	-	expression tag
Glu 108	-	expression tag
His 109	-	expression tag
His 110	-	expression tag
His 111	-	expression tag
His 112	-	expression tag
His 113	-	expression tag
His 114	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	121676.3
Non-Polymers*	Number of molecules	5
	Total formula weight	540.3
All*	Total formula weight	122216.6

*Water molecules are not included.