9TOY
Investigating the binding mechanism of Interferon Regulatory Factor 4 to DNA in the context of Multiple Myeloma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F (A, B, D, F) | Interferon regulatory factor 4 | polymer | 123 | 14243.2 | 4 | UniProt (Q15306) Pfam (PF00605) | Homo sapiens (human) | IRF-4,Lymphocyte-specific interferon regulatory factor,LSIRF,Multiple myeloma oncogene 1,NF-EM5 |
| 2 | C, G (C, G) | DNA (5'-D(P*TP*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*TP*GP*AP*GP*AP*AP*AP*GP*C)-3') | polymer | 20 | 6160.0 | 2 | Homo sapiens | ||
| 3 | D, H (E, H) | DNA (5'-D(P*AP*GP*CP*TP*TP*TP*CP*TP*CP*AP*GP*TP*TP*TP*CP*AP*GP*TP*TP*G)-3') | polymer | 20 | 6105.9 | 2 | Homo sapiens | ||
| 4 | I, J, K, L, M (A, B, C, G) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 5 | N, O, P, Q, R... (A, B, C, E, D...) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A, B, D, F: 20 - 139 (UniProt: Q15306)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Gly 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 81504.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 200.4 | |
| All* | Total formula weight | 81705.0 |
