9TOE
CTX-M-15 class A beta-lactamase mixed with avibactam for 3 hours, then washed for 50 s, cryo crystal structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 265 | 28293.0 | 1 | UniProt (G3G192) | Klebsiella pneumoniae | |
| 2 | B (A) | (2S,5R)-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide | non-polymer | 265.2 | 1 | Chemie (FYG) PubChem (9835049) | |||
| 3 | C (A) | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide | non-polymer | 267.3 | 1 | Chemie (NXL) PubChem (132451794) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | E, F (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 7 | H, I (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 8 | J (A) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence modifications
A: 26 - 288 (UniProt: G3G192)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
| Pro 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28293.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 898.2 | |
| All* | Total formula weight | 29191.1 |
