9TNS

GABA-A receptor a3b3g2 + GABA-PRE + a3NB83

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Gamma-aminobutyric acid receptor subunit alpha-3	polymer	382	43382.8	2	UniProt (P34903)	Homo sapiens (human)	GABA(A) receptor subunit alpha-3,GABAAR subunit alpha-3
2	B, E (B, E)	GABA-A receptor beta-3-bril	polymer	451	51615.1	2		Homo sapiens
3	C (C)	Gamma-aminobutyric acid receptor subunit gamma-2	polymer	371	42798.9	1	UniProt (P18507)	Homo sapiens (human)	GABA(A) receptor subunit gamma-2,GABAAR subunit gamma-2
4	F (F)	a3NB83	polymer	133	14582.1	1		Lama glama
5	G (H)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	1	In PDB GlyTouCan (G55220VL)
6	H, K (J, O)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
7	I, L (K, P)	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	2	In PDB GlyTouCan (G09724ZC)
8	J (M)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
9	M, N, P, Q, R (A, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG) PubChem (24139)
10	O, S (B, E)	GAMMA-AMINO-BUTANOIC ACID	non-polymer		103.1	2	Chemie (ABU) PubChem (119)

Sequence modifications

A, D: 1 - 336 (UniProt: P34903)
A, D: 426 - 464 (UniProt: P34903)

PDB	External Database	Details
Ser 337	-	linker
Gln 338	-	linker
Pro 339	-	linker
Ala 340	-	linker
Arg 341	-	linker
Ala 342	-	linker
Ala 343	-	linker

C: 1 - 322 (UniProt: P18507)

PDB	External Database	Details
Thr 11	Ala 50	conflict

C: 408 - 436 (UniProt: P18507)

PDB	External Database	Details
Ser 402	-	linker
Gln 403	-	linker
Pro 404	-	linker
Ala 405	-	linker
Arg 406	-	linker
Ala 407	-	linker
Gly 437	-	expression tag
Thr 438	-	expression tag
Gly 439	-	expression tag
Thr 440	-	expression tag
Gly 441	-	expression tag
Thr 442	-	expression tag
Glu 443	-	expression tag
Thr 444	-	expression tag
Ser 445	-	expression tag
Gln 446	-	expression tag
Val 447	-	expression tag
Ala 448	-	expression tag
Pro 449	-	expression tag
Ala 450	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	247376.7
Branched	Number of molecules	6
	Total formula weight	5140.7
Non-Polymers*	Number of molecules	7
	Total formula weight	1312.3
All*	Total formula weight	253829.6

*Water molecules are not included.