9TMX
Crystal structure of M. tuberculosis PknA in complex with AZD-5438
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase PknA | polymer | 284 | 30536.1 | 1 | UniProt (P9WI83) Pfam (PF00069) | Mycobacterium tuberculosis | |
| 2 | B (A) | 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine | non-polymer | 371.5 | 1 | Chemie (FB8) PubChem (16747683) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence modifications
A: 1 - 283 (UniProt: P9WI83)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30536.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 467.5 | |
| All* | Total formula weight | 31003.6 |
