9TML
Structure of TCR-B targeting GPC3 [FLAELAYDL] peptide bound to HLA-A*02:01
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class I antigen | polymer | 280 | 32313.7 | 1 | UniProt (A5I8L1) | Homo sapiens (human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 101 | 11936.4 | 1 | UniProt (P61769) | Homo sapiens (human) | |
| 3 | C (C) | TCR-B alpha chain | polymer | 213 | 23818.4 | 1 | Homo sapiens | ||
| 4 | D (D) | TCR-B beta chain | polymer | 244 | 27749.2 | 1 | Homo sapiens | ||
| 5 | E (P) | Glypican-3 beta subunit | polymer | 9 | 1054.2 | 1 | UniProt (P51654) | Homo sapiens (human) | |
| 6 | F, G, L, R, S (A, C) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) PubChem (753) | |||
| 7 | H, I, J, K, N... (A, B, C) | SODIUM ION | non-polymer | 23.0 | 7 | Chemie (NA) PubChem (923) | |||
| 8 | M (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) PubChem (4478249) | |||
| 9 | P (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) PubChem (24139) | |||
| 10 | T, U, V, W, X (A, B, C, D, P) | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 2 - 279 (UniProt: A5I8L1)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | initiating methionine |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 96871.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1037.8 | |
| All* | Total formula weight | 97909.7 |
