9TLW
De novo designed single-chain antiparallel coiled-coil hairpin with binding site for MCL-1, Sc-apCC-2-MCL-1-4 in complex with MCL-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Sc-apCC-2-MCL-1-4 | polymer | 75 | 8557.7 | 2 | synthetic construct | ||
| 2 | B, D (B, D) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 156 | 17765.2 | 2 | UniProt (Q07820) | Homo sapiens (human) | |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
B, D: 1 - 155 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 52645.8 | |
| All* | Total formula weight | 52645.8 |
