9TL4
Crystal structure of Haemonchus contortus DAF-12 ligand binding domain in complex with a coactivator peptide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear hormone receptor DAF-12 | polymer | 247 | 28411.7 | 1 | UniProt (A0A7I4Z2W0) | Haemonchus contortus (barber pole worm) | |
| 2 | B (B) | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) | Homo sapiens | |
| 3 | C, D (A) | MALONATE ION | non-polymer | 102.0 | 2 | Chemie (MLI) PubChem (9084) | |||
| 4 | E (A) | (2~{S},6~{R})-6-[(8~{S},9~{S},10~{R},13~{R},14~{S},17~{R})-10,13-dimethyl-3-oxidanylidene-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-heptanoic acid | non-polymer | 414.6 | 1 | Chemie (A1JWE) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 428 - 670 (UniProt: A0A7I4Z2W0)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Ser 538 | Cys 538 | engineered mutation |
| Ser 592 | Cys 592 | engineered mutation |
| Ser 610 | Cys 610 | engineered mutation |
| Ser 646 | Cys 646 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29991.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 618.7 | |
| All* | Total formula weight | 30610.3 |
