9TG6

Cryo-EM structure of the inward rectifying potassium channel 7.1 (Kir7.1) in complex with PIP2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, D, C)	Inward rectifier potassium channel 13	polymer	375	42377.3	4	UniProt (O60928)	Homo sapiens (human)	Inward rectifier K(+) channel Kir7.1,Potassium channel,inwardly rectifying subfamily J member 13
2	E, J, K, L (A, B, D, C)	[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate	non-polymer		746.6	4	Chemie (PIO)
3	F, G, H, I (A, B)	POTASSIUM ION	non-polymer		39.1	4	Chemie (K) PubChem (813)

Sequence modifications

A, B, D, C: 0 - 360 (UniProt: O60928)

PDB	External Database	Details
Asp -10	-	expression tag
Tyr -9	-	expression tag
Lys -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Lys -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Glu 361	-	expression tag
Asn 362	-	expression tag
Leu 363	-	expression tag
Tyr 364	-	expression tag
Phe 365	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	169509.0
Non-Polymers*	Number of molecules	8
	Total formula weight	3142.7
All*	Total formula weight	172651.7

*Water molecules are not included.