9TG1
Structure of endogenous human ncBAF bound to nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (K) | Transcription activator BRG1 | polymer | 1647 | 184923.8 | 1 | UniProt (P51532) | Homo sapiens (human) | ATP-dependent helicase SMARCA4,BRG1-associated factor 190A,BAF190A,Mitotic growth and transcription activator,Protein BRG-1,Protein brahma homolog 1,SNF2-beta,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 |
| 2 | B, F (A, E) | Histone H3.2 | polymer | 136 | 15421.1 | 2 | UniProt (P84233) | Xenopus laevis (African clawed frog) | |
| 3 | C, G (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62799) | Xenopus laevis (African clawed frog) | |
| 4 | D, H (C, G) | Histone H2A type 1 | polymer | 130 | 14093.4 | 2 | UniProt (P06897) | Xenopus laevis (African clawed frog) | |
| 5 | E, I (D, H) | Histone H2B 1.1 | polymer | 126 | 13979.3 | 2 | UniProt (P02281) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 6 | J (I) | DNA (131-MER) | polymer | 131 | 40210.6 | 1 | unidentified plasmid | ||
| 7 | K (J) | DNA (131-MER) | polymer | 131 | 40650.9 | 1 | unidentified plasmid | ||
| 8 | L (L) | Bromodomain-containing protein 9 | polymer | 597 | 67112.2 | 1 | UniProt (Q9H8M2) | Homo sapiens (human) | Rhabdomyosarcoma antigen MU-RMS-40.8 |
| 9 | M (O) | B-cell CLL/lymphoma 7 protein family member A | polymer | 210 | 22842.9 | 1 | UniProt (Q4VC05) | Homo sapiens (human) | |
| 10 | N (M) | Actin, cytoplasmic 1, N-terminally processed | polymer | 375 | 41782.7 | 1 | UniProt (P60709) | Homo sapiens (human) | |
| 11 | O (N) | Actin-like protein 6A | polymer | 429 | 47509.8 | 1 | UniProt (O96019) | Homo sapiens (human) | 53 kDa BRG1-associated factor A,Actin-related protein Baf53a,ArpNbeta,BRG1-associated factor 53A,BAF53A,INO80 complex subunit K |
| 12 | P (K) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 13 | Q (K) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 14 | R (K) | BERYLLIUM TRIFLUORIDE ION | non-polymer | 66.0 | 1 | Chemie (BEF) |
Sequence modifications
C, G: 0 - 129 (UniProt: P06897)
D, H: -3 - 122 (UniProt: P02281)
L: 1 - 597 (UniProt: Q9H8M2)
| PDB | External Database | Details |
|---|---|---|
| Arg 99 | Gly 100 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Thr 29 | Ser 33 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Glu 240 | Gln 240 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 554809.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 517.5 | |
| All* | Total formula weight | 555327.0 |
