9TFU
Crystal structure of beta-TrCP bound by monophosphorylated ATF4 degron peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | F-box/WD repeat-containing protein 1A | polymer | 365 | 41829.7 | 1 | UniProt (Q9Y297) | Homo sapiens (human) | E3RSIkappaB,Epididymis tissue protein Li 2a,F-box and WD repeats protein beta-TrCP,pIkappaBalpha-E3 receptor subunit |
| 2 | B (B) | Cyclic AMP-dependent transcription factor ATF-4 | polymer | 13 | 1421.4 | 1 | UniProt (P18848) | Homo sapiens (human) | cAMP-dependent transcription factor ATF-4,Activating transcription factor 4,Cyclic AMP-responsive element-binding protein 2,CREB-2,cAMP-responsive element-binding protein 2,Tax-responsive enhancer element-binding protein 67,TaxREB67 |
| 3 | C, D (A, B) | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A: 186 - 548 (UniProt: Q9Y297)
| PDB | External Database | Details |
|---|---|---|
| Gly 184 | - | expression tag |
| Ser 185 | - | expression tag |
| Glu 188 | Leu 224 | engineered mutation |
| Glu 192 | Leu 228 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43251.1 | |
| All* | Total formula weight | 43251.1 |
