9TES
Crystal structure of beta-TrCP bound by diphosphorylated PDCD4 degron peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | F-box/WD repeat-containing protein 1A | polymer | 365 | 41829.7 | 1 | UniProt (Q9Y297) | Homo sapiens (human) | E3RSIkappaB,Epididymis tissue protein Li 2a,F-box and WD repeats protein beta-TrCP,pIkappaBalpha-E3 receptor subunit |
| 2 | B (B) | Programmed cell death protein 4 | polymer | 13 | 1486.2 | 1 | UniProt (Q53EL6) | Homo sapiens (human) | Neoplastic transformation inhibitor protein,Nuclear antigen H731-like,Protein 197/15a |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 186 - 548 (UniProt: Q9Y297)
| PDB | External Database | Details |
|---|---|---|
| Gly 184 | - | expression tag |
| Ser 185 | - | expression tag |
| Glu 188 | Leu 224 | engineered mutation |
| Glu 192 | Leu 228 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43316.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 86.4 | |
| All* | Total formula weight | 43402.3 |
