9TD5

ERAP1 in complex with 1-[2-(5-chloro-2-oxo-2,3-dihydro-1,3-benzothiazol-3-yl)acetamido]cyclohexane-1-carboxylic acid

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Endoplasmic reticulum aminopeptidase 1	polymer	922	105371.4	1	UniProt (Q9NZ08) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838)	Homo sapiens (human)	ARTS-1,Adipocyte-derived leucine aminopeptidase,A-LAP,Aminopeptidase PILS,Puromycin-insensitive leucyl-specific aminopeptidase,PILS-AP,Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN) PubChem (32051)
3	C (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4) PubChem (1061)
4	D, E, F, G, H... (A)	1,2-ETHANEDIOL	non-polymer		62.1	10	Chemie (EDO)
5	N (A)	1-[2-(5-chloranyl-2-oxidanylidene-1,3-benzothiazol-3-yl)ethanoylamino]cyclohexane-1-carboxylic acid	non-polymer		368.8	1	Chemie (A1JVH)
6	O (A)	water	water		18.0	1346	Chemie (HOH)

Sequence modifications

A: 1 - 485 (UniProt: Q9NZ08)

PDB	External Database	Details
Gln 70	Asn 70	conflict
Gln 154	Asn 154	conflict
Gln 414	Asn 414	conflict

A: 514 - 941 (UniProt: Q9NZ08)

PDB	External Database	Details
Gly 486	-	linker
Ser 487	-	linker
Gly 513	-	linker
Arg 528	Lys 528	conflict
Gln 760	Asn 760	conflict
Glu 942	-	expression tag
Asn 943	-	expression tag
Leu 944	-	expression tag
Tyr 945	-	expression tag
Phe 946	-	expression tag
Gln 947	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	105371.4
Non-Polymers*	Number of molecules	13
	Total formula weight	1149.9
All*	Total formula weight	106521.3

*Water molecules are not included.