9TAZ
OXA-48: Q5 mutant in an acyl enzyme complex with piperacillin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 244 | 28188.9 | 1 | UniProt (D6QY24) | Klebsiella pneumoniae | |
| 2 | B, C, D, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 3 | E (A) | Piperacillin (Open Form) | non-polymer | 519.6 | 1 | Chemie (JPP) PubChem (78225432) | |||
| 4 | F, G (A) | Hydrolyzed piperacillin | non-polymer | 535.6 | 2 | Chemie (YPP) PubChem (54669584) | |||
| 5 | I, J (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 6 | K (A) | water | water | 18.0 | 220 | Chemie (HOH) |
Sequence modifications
A: 23 - 265 (UniProt: D6QY24)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Val 33 | Ala 33 | engineered mutation |
| Glu 51 | Lys 51 | engineered mutation |
| Leu 72 | Phe 72 | engineered mutation |
| Ala 212 | Ser 212 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28188.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1909.9 | |
| All* | Total formula weight | 30098.8 |
