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9T99

Structure of C. elegans Dicer-related helicase 1 (DRH1) bound to blunt end 5'P-dsRNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dicer-related helicasepolymer72883006.51UniProt (G5EDI8)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF11648)
Caenorhabditis elegansRNA helicase
2B
(S)
RNA (5'-R(P*GP*GP*UP*AP*GP*UP*CP*UP*AP*CP*C)-3')polymer113483.11synthetic construct
3C, D
(X, Y)
RNA (5'-R(P*GP*GP*UP*AP*GP*CP*GP*CP*UP*AP*CP*C)-3')polymer123827.32synthetic construct
4E
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5F
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
6G, H, I
(A, X, Y)
waterwater18.080Chemie (HOH)
Sequence modifications
A: 291 - 1017 (UniProt: G5EDI8)
PDBExternal DatabaseDetails
Gly 290-expression tag
Gln 431Glu 431engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight94144.3
Non-Polymers*Number of molecules2
Total formula weight492.6
All*Total formula weight94636.9
*Water molecules are not included.

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PDB entries from 2026-03-11

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