9T8Y
Crystal structure of beta-TrCP bound by monophosphorylated NRF2 degron peptide.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | F-box/WD repeat-containing protein 1A | polymer | 365 | 41829.7 | 1 | UniProt (Q9Y297) | Homo sapiens (human) | E3RSIkappaB,Epididymis tissue protein Li 2a,F-box and WD repeats protein beta-TrCP,pIkappaBalpha-E3 receptor subunit |
| 2 | B (B) | Nuclear factor erythroid 2-related factor 2 | polymer | 12 | 1289.2 | 1 | UniProt (Q16236) | Homo sapiens (human) | NF-E2-related factor 2,NFE2-related factor 2,Nrf-2,Nuclear factor,erythroid derived 2,like 2 |
| 3 | C, D (A, B) | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence modifications
A: 186 - 548 (UniProt: Q9Y297)
| PDB | External Database | Details |
|---|---|---|
| Gly 184 | - | expression tag |
| Ser 185 | - | expression tag |
| Glu 188 | Leu 224 | engineered mutation |
| Glu 192 | Leu 228 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43118.9 | |
| All* | Total formula weight | 43118.9 |
