9T6K
Crystal structure of wild-type c-MET bound by glumetinib.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hepatocyte growth factor receptor | polymer | 296 | 33471.9 | 1 | UniProt (P08581) Pfam (PF07714) | Homo sapiens (human) | HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met |
| 2 | B (A) | Glumetinib | non-polymer | 459.5 | 1 | Chemie (A1JT6) | |||
| 3 | C, E (A) | POLYETHYLENE GLYCOL (N=34) | non-polymer | 1529.8 | 2 | Chemie (15P) | |||
| 4 | D (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | F (A) | water | water | 18.0 | 324 | Chemie (HOH) |
Sequence modifications
A: 1052 - 1346 (UniProt: P08581)
| PDB | External Database | Details |
|---|---|---|
| Gly 1051 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33471.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 3625.3 | |
| All* | Total formula weight | 37097.1 |
