9T4K
Human Diphosphoinositol Polyphosphate Phosphohydrolase 1 (DIPP1) H91M mutant in complex with IP6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Diphosphoinositol polyphosphate phosphohydrolase 1 | polymer | 148 | 17108.4 | 1 | UniProt (O95989) | Homo sapiens (human) | DIPP-1,Diadenosine hexaphosphate hydrolase,Ap6A hydrolase,Endopolyphosphatase,Nucleoside diphosphate-linked moiety X motif 3,Nudix motif 3,m7GpppN-mRNA hydrolase,m7GpppX diphosphatase |
| 2 | B (A) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 3 | C, G (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) PubChem (1061) | |||
| 4 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 7 | I (A) | water | water | 18.0 | 187 | Chemie (HOH) |
Sequence modifications
A: 1 - 148 (UniProt: O95989)
| PDB | External Database | Details |
|---|---|---|
| Met 91 | His 91 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17108.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 996.1 | |
| All* | Total formula weight | 18104.5 |
