9T4D
Human Diphosphoinositol Polyphosphate Phosphohydrolase 1 (DIPP1) R41A mutant in complex with 5-(PP)-IP5 (5-IP7)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Diphosphoinositol polyphosphate phosphohydrolase 1 | polymer | 148 | 17029.3 | 1 | UniProt (O95989) | Homo sapiens (human) | DIPP-1,Diadenosine hexaphosphate hydrolase,Ap6A hydrolase,Endopolyphosphatase,Nucleoside diphosphate-linked moiety X motif 3,Nudix motif 3,m7GpppN-mRNA hydrolase,m7GpppX diphosphatase |
| 2 | B (A) | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate | non-polymer | 740.0 | 1 | Chemie (I7P) | |||
| 3 | C, D, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 4 | G, H, I (A) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) PubChem (1061) | |||
| 5 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | K (A) | FLUORIDE ION | non-polymer | 19.0 | 1 | Chemie (F) PubChem (28179) | |||
| 7 | L (A) | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A: 1 - 148 (UniProt: O95989)
| PDB | External Database | Details |
|---|---|---|
| Ala 41 | Arg 41 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17029.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1176.6 | |
| All* | Total formula weight | 18205.8 |
