9T4B
Human Diphosphoinositol Polyphosphate Phosphohydrolase 1 (DIPP1) R89S mutant in complex with 1,5-(PCP)-IP5 (PCP-IP8)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Diphosphoinositol polyphosphate phosphohydrolase 1 | polymer | 148 | 17045.3 | 1 | UniProt (O95989) | Homo sapiens (human) | DIPP-1,Diadenosine hexaphosphate hydrolase,Ap6A hydrolase,Endopolyphosphatase,Nucleoside diphosphate-linked moiety X motif 3,Nudix motif 3,m7GpppN-mRNA hydrolase,m7GpppX diphosphatase |
| 2 | B (A) | {[(1R,3S,4S,5R,6S)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl]bis[oxy(hydroxyphosphoryl)methanediyl]}bis(phosphonic acid) | non-polymer | 816.0 | 1 | Chemie (4WZ) | |||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D, E, G, H (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 5 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | I (A) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A: 1 - 148 (UniProt: O95989)
| PDB | External Database | Details |
|---|---|---|
| Ser 89 | Arg 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17045.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1010.8 | |
| All* | Total formula weight | 18056.0 |
