9T0E
Structure of Crimean Congo hemorrhagic fever virus (CCHFV) L protein bound to 5' vRNA and nanobody 20096.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Nanobody 20096 | polymer | 130 | 14180.8 | 1 | Lama glama | ||
| 2 | B (R) | RNA (5'-R(P*UP*CP*UP*CP*AP*AP*AP*GP*AP*UP*AP*UP*A)-3') | polymer | 16 | 5090.1 | 1 | Crimean-Congo hemorrhagic fever virus strain IbAr10200 | ||
| 3 | C (A) | RNA-directed RNA polymerase L | polymer | 3990 | 453487.0 | 1 | UniProt (Q6TQR6) | Crimean-Congo hemorrhagic fever virus strain IbAr10200 | Protein L,Large structural protein,Replicase,Transcriptase |
| 4 | D, E (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) PubChem (32051) | |||
| 5 | F, G (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | H, I, J (C, R, A) | water | water | 18.0 | 293 | Chemie (HOH) |
Sequence modifications
A: 1 - 3945 (UniProt: Q6TQR6)
| PDB | External Database | Details |
|---|---|---|
| Met -44 | - | initiating methionine |
| Trp -43 | - | expression tag |
| Ser -42 | - | expression tag |
| His -41 | - | expression tag |
| Pro -40 | - | expression tag |
| Gln -39 | - | expression tag |
| Phe -38 | - | expression tag |
| Glu -37 | - | expression tag |
| Lys -36 | - | expression tag |
| Gly -35 | - | expression tag |
| Gly -34 | - | expression tag |
| Gly -33 | - | expression tag |
| Ser -32 | - | expression tag |
| Gly -31 | - | expression tag |
| Gly -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Ser -28 | - | expression tag |
| Gly -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Ser -25 | - | expression tag |
| Ser -24 | - | expression tag |
| Ala -23 | - | expression tag |
| Trp -22 | - | expression tag |
| Ser -21 | - | expression tag |
| His -20 | - | expression tag |
| Pro -19 | - | expression tag |
| Gln -18 | - | expression tag |
| Phe -17 | - | expression tag |
| Glu -16 | - | expression tag |
| Lys -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 1047 | Glu 1047 | conflict |
| Pro 1660 | Thr 1660 | conflict |
| Thr 1675 | Asn 1675 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 472757.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 179.4 | |
| All* | Total formula weight | 472937.3 |
