9T09
X-ray structure of the catalytic domain of CDC25B C473S at 1.34 angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | M-phase inducer phosphatase 2 | polymer | 197 | 22995.3 | 1 | UniProt (P30305) | Homo sapiens (human) | Dual specificity phosphatase Cdc25B |
| 2 | B, C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | G (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | H, I, J (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | K (A) | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A: 377 - 550 (UniProt: P30305)
| PDB | External Database | Details |
|---|---|---|
| Met 354 | - | initiating methionine |
| Gly 355 | - | expression tag |
| Ser 356 | - | expression tag |
| Ser 357 | - | expression tag |
| His 358 | - | expression tag |
| His 359 | - | expression tag |
| His 360 | - | expression tag |
| His 361 | - | expression tag |
| His 362 | - | expression tag |
| His 363 | - | expression tag |
| Ser 364 | - | expression tag |
| Ser 365 | - | expression tag |
| Gly 366 | - | expression tag |
| Leu 367 | - | expression tag |
| Val 368 | - | expression tag |
| Pro 369 | - | expression tag |
| Arg 370 | - | expression tag |
| Gly 371 | - | expression tag |
| Ser 372 | - | expression tag |
| His 373 | - | expression tag |
| Met 374 | - | expression tag |
| Ala 375 | - | expression tag |
| Ser 376 | - | expression tag |
| Ser 473 | Cys 487 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22995.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 761.4 | |
| All* | Total formula weight | 23756.7 |
