9SZQ
Crystal structure of the E336K mutant of human Apoptosis Inducing Factor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Apoptosis-inducing factor 1, mitochondrial | polymer | 535 | 58279.1 | 1 | UniProt (O95831) Pfam (PF00070) Pfam (PF14721) | Homo sapiens (human) | Programmed cell death protein 8 |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 4 | D (A) | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence modifications
A: 102 - 613 (UniProt: O95831)
| PDB | External Database | Details |
|---|---|---|
| Met 79 | - | initiating methionine |
| Gly 80 | - | expression tag |
| Ser 81 | - | expression tag |
| Ser 82 | - | expression tag |
| His 83 | - | expression tag |
| His 84 | - | expression tag |
| His 85 | - | expression tag |
| His 86 | - | expression tag |
| His 87 | - | expression tag |
| His 88 | - | expression tag |
| Gly 89 | - | expression tag |
| Ser 90 | - | expression tag |
| Ser 91 | - | expression tag |
| Leu 92 | - | expression tag |
| Val 93 | - | expression tag |
| Pro 94 | - | expression tag |
| Arg 95 | - | expression tag |
| Gly 96 | - | expression tag |
| Ser 97 | - | expression tag |
| Gly 98 | - | expression tag |
| Ser 99 | - | expression tag |
| Ser 100 | - | expression tag |
| Lys 101 | - | expression tag |
| Lys 336 | Glu 336 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58279.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 877.6 | |
| All* | Total formula weight | 59156.8 |
