9SYN
Crystal structure of TEAD4 in complex with Vgll1-peptide and IAG933
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcriptional enhancer factor TEF-3 | polymer | 220 | 25597.8 | 1 | UniProt (Q15561) | Homo sapiens (human) | TEA domain family member 4,TEAD-4,Transcription factor 13-like 1,Transcription factor RTEF-1 |
| 2 | B (B) | Transcription cofactor vestigial-like protein 1 | polymer | 18 | 1931.1 | 1 | UniProt (Q99NC0) | Mus musculus | Vgl-1,Vestigial-related factor |
| 3 | C (A) | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | Homo sapiens | ||
| 4 | D (A) | 4-[(2~{S})-5-chloranyl-6-fluoranyl-2-phenyl-2-[(2~{S})-pyrrolidin-2-yl]-3~{H}-1-benzofuran-4-yl]-5-fluoranyl-6-(2-hydroxyethyloxy)-~{N}-methyl-pyridine-3-carboxamide | non-polymer | 530.0 | 1 | Chemie (WCF) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
A: 217 - 434 (UniProt: Q15561)
B: 36 - 51 (UniProt: Q99NC0)
| PDB | External Database | Details |
|---|---|---|
| Gly 215 | - | expression tag |
| Pro 216 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 35 | - | acetylation |
| Nh2 52 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27529.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 758.3 | |
| All* | Total formula weight | 28287.3 |
