9SXW

Crystal structure of ERK2 in complex with a ligand

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Mitogen-activated protein kinase 1	polymer	364	42235.5	1	UniProt (P63086) Pfam (PF00069)	Rattus norvegicus (Norway rat)
2	B (A)	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS) PubChem (679)
3	C (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4	D (A)	~{N}-[(1~{S})-2-oxidanyl-1-phenyl-ethyl]-5-(5-thiophen-3-yl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)-1~{H}-pyrrole-3-carboxamide	non-polymer		428.5	1	Chemie (A1JRH)
5	E (A)	water	water		18.0	132	Chemie (HOH)

Sequence modifications

A: 1 - 358 (UniProt: P63086)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42235.5
Non-Polymers*	Number of molecules	3
	Total formula weight	602.7
All*	Total formula weight	42838.2

*Water molecules are not included.