9SXS

Crystal structure of ERK2 in complex with a ligand

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Mitogen-activated protein kinase 1	polymer	364	42235.5	1	UniProt (P63086) Pfam (PF00069)	Rattus norvegicus (Norway rat)
2	B, C (A)	DIMETHYL SULFOXIDE	non-polymer		78.1	2	Chemie (DMS) PubChem (679)
3	D (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4	E (A)	~{N}-[3-[5-[4-(hydroxymethyl)phenyl]-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]-1~{H}-pyrazol-5-yl]-3-(4-methoxyphenyl)propanamide	non-polymer		467.5	1	Chemie (A1JRK)
5	F (A)	water	water		18.0	193	Chemie (HOH)

Sequence modifications

A: 1 - 358 (UniProt: P63086)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42235.5
Non-Polymers*	Number of molecules	4
	Total formula weight	719.8
All*	Total formula weight	42955.4

*Water molecules are not included.