9SUL
CRYO-EM STRUCTURE OF TRYPANOSOMA BRUCEI BLOODSTREAM FORM 80S RIBOSOME
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (Et) | E-SITE TRNA | polymer | 95 | 30637.2 | 1 | Trypanosoma brucei brucei | ||
| 2 | B (A0) | 40S ribosomal protein S3a | polymer | 256 | 29477.3 | 1 | UniProt (Q38BK6) Pfam (PF01015) | Trypanosoma brucei brucei | |
| 3 | C (A1) | 40S ribosomal protein S4 | polymer | 273 | 30704.2 | 1 | UniProt (Q386F2) Pfam (PF08071) Pfam (PF01479) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) | Trypanosoma brucei brucei | |
| 4 | D (A2) | 40S ribosomal protein S5, putative | polymer | 190 | 21424.9 | 1 | UniProt (Q385D9) Pfam (PF00177) | Trypanosoma brucei brucei | |
| 5 | E (A3) | 40S ribosomal protein S6 | polymer | 250 | 28507.4 | 1 | UniProt (Q38CL9) Pfam (PF01092) | Trypanosoma brucei brucei | |
| 6 | F (A4) | 40S ribosomal protein S7 | polymer | 202 | 23934.2 | 1 | UniProt (Q38FD9) Pfam (PF01251) | Trypanosoma brucei brucei | |
| 7 | G (A5) | 40S ribosomal protein S8 | polymer | 220 | 25001.4 | 1 | UniProt (Q57YL6) Pfam (PF01201) | Trypanosoma brucei brucei | |
| 8 | H (A6) | Probable 40S ribosomal protein S9 | polymer | 190 | 22098.7 | 1 | UniProt (P17959) | Trypanosoma brucei brucei | |
| 9 | I (A7) | Small ribosomal subunit protein RACK1 | polymer | 318 | 34756.8 | 1 | UniProt (P69103) | Trypanosoma brucei brucei | Activated protein kinase C receptor homolog,Guanine nucleotide-binding protein subunit beta-like protein |
| 10 | J (A8) | Putative ribosomal protein S29 | polymer | 57 | 6745.0 | 1 | UniProt (G0UD55) | Trypanosoma brucei brucei | |
| 11 | K (A9) | Ubiquitin-60S ribosomal protein L40 | polymer | 153 | 16936.7 | 1 | UniProt (Q57WI3) Pfam (PF00240) Pfam (PF01599) | Trypanosoma brucei brucei | |
| 12 | L (AA) | SSU rRNA | polymer | 2280 | 734203.6 | 1 | Trypanosoma brucei brucei | ||
| 13 | M (AC) | 40S ribosomal protein SA | polymer | 277 | 31396.0 | 1 | UniProt (Q383I8) Pfam (PF00318) | Trypanosoma brucei brucei | |
| 14 | N (AD) | 40S ribosomal protein S10, putative | polymer | 172 | 19322.8 | 1 | UniProt (Q38B66) Pfam (PF03501) | Trypanosoma brucei brucei | |
| 15 | O (AE) | 40S ribosomal proteins S11, putative | polymer | 174 | 20132.5 | 1 | UniProt (Q38CI4) Pfam (PF16205) Pfam (PF00366) | Trypanosoma brucei brucei | |
| 16 | P (AF) | Small ribosomal subunit protein eS12 | polymer | 144 | 15918.2 | 1 | UniProt (Q03253) | Trypanosoma brucei brucei | 40S ribosomal protein S12 |
| 17 | Q (AG) | 40S ribosomal protein S13, putative | polymer | 151 | 17347.6 | 1 | UniProt (Q586C2) Pfam (PF08069) Pfam (PF00312) | Trypanosoma brucei brucei | |
| 18 | R (AH) | Small ribosomal subunit protein uS11 | polymer | 144 | 15540.9 | 1 | UniProt (P19800) | Trypanosoma brucei brucei | 40S ribosomal protein S14 |
| 19 | S (AI) | 40S ribosomal protein S15, putative | polymer | 152 | 17512.4 | 1 | UniProt (Q57XN7) Pfam (PF00203) | Trypanosoma brucei brucei | |
| 20 | T (AJ) | 40S ribosomal protein S15a, putative | polymer | 130 | 14669.3 | 1 | UniProt (Q580K6) Pfam (PF00410) | Trypanosoma brucei brucei | |
| 21 | U (AK) | 40S ribosomal protein S16, putative | polymer | 149 | 17048.0 | 1 | UniProt (Q57VV0) Pfam (PF00380) | Trypanosoma brucei brucei | |
| 22 | V (AL) | 40S ribosomal protein S17, putative | polymer | 142 | 16259.2 | 1 | UniProt (Q382Z8) Pfam (PF00833) | Trypanosoma brucei brucei | |
| 23 | W (AM) | 40S ribosomal protein S18, putative | polymer | 153 | 17548.5 | 1 | UniProt (Q38B69) Pfam (PF00416) | Trypanosoma brucei brucei | |
| 24 | X (AO) | Ribosomal protein S19, putative | polymer | 167 | 18891.5 | 1 | UniProt (Q583K7) Pfam (PF01090) | Trypanosoma brucei brucei | |
| 25 | Y (AP) | 40S ribosomal protein S2, putative | polymer | 266 | 28688.1 | 1 | UniProt (Q388D3) Pfam (PF00333) Pfam (PF03719) | Trypanosoma brucei brucei | |
| 26 | Z (AQ) | Small ribosomal subunit protein uS10 | polymer | 117 | 13377.6 | 1 | UniProt (A0A3L6KWF3) | Trypanosoma brucei brucei | |
| 27 | AA (AR) | 40S ribosomal protein S21, putative | polymer | 194 | 21185.7 | 1 | UniProt (Q385B8) Pfam (PF01249) | Trypanosoma brucei brucei | |
| 28 | BA (AS) | 40S ribosomal protein S23, putative | polymer | 143 | 15979.7 | 1 | UniProt (Q38CD1) Pfam (PF00164) | Trypanosoma brucei brucei | |
| 29 | CA (AT) | 40S ribosomal protein S24 | polymer | 137 | 15722.8 | 1 | UniProt (Q38AM9) Pfam (PF01282) | Trypanosoma brucei brucei | |
| 30 | DA (AU) | 40S ribosomal protein S25 | polymer | 113 | 12589.1 | 1 | UniProt (Q57XX0) Pfam (PF03297) | Trypanosoma brucei brucei | |
| 31 | EA (AV) | 40S ribosomal protein S26 | polymer | 111 | 12837.2 | 1 | UniProt (Q384J9) Pfam (PF01283) | Trypanosoma brucei brucei | |
| 32 | FA (AW) | 40S ribosomal protein S27, putative | polymer | 86 | 9648.3 | 1 | UniProt (Q383V7) Pfam (PF01667) | Trypanosoma brucei brucei | |
| 33 | GA (AX) | 40S ribosomal protein S3, putative | polymer | 214 | 24259.4 | 1 | UniProt (Q38EW1) Pfam (PF07650) Pfam (PF00189) | Trypanosoma brucei brucei | |
| 34 | HA (AY) | 40S ribosomal protein S30 | polymer | 66 | 7454.9 | 1 | UniProt (Q584U5) Pfam (PF04758) | Trypanosoma brucei brucei | |
| 35 | IA (AZ) | 40S ribosomal protein S33, putative | polymer | 103 | 11186.9 | 1 | UniProt (Q57U30) Pfam (PF01200) | Trypanosoma brucei brucei | |
| 36 | JA (Az) | RNA-binding protein | polymer | 279 | 30340.9 | 1 | UniProt (Q382D5) Pfam (PF00076) | Trypanosoma brucei brucei | |
| 37 | KA (BA) | LSUa rRNA | polymer | 1866 | 602633.4 | 1 | Trypanosoma brucei brucei | ||
| 38 | LA (BB) | LSUb rRNA | polymer | 1544 | 497231.7 | 1 | Trypanosoma brucei brucei | ||
| 39 | MA (BC) | 5.8S rRNA | polymer | 209 | 67019.7 | 1 | GenBank (10527) | Trypanosoma brucei brucei | |
| 40 | NA (BD) | 5S rRNA | polymer | 120 | 38621.9 | 1 | GenBank (162230) | Trypanosoma brucei brucei | |
| 41 | OA (BE) | SrRNA-1 | polymer | 217 | 69461.9 | 1 | GenBank (10528) | Trypanosoma brucei brucei | |
| 42 | PA (BF) | SrRNA-6 | polymer | 78 | 24646.5 | 1 | GenBank (62359081) | Trypanosoma brucei brucei | |
| 43 | QA (BG) | SrRNA-2 | polymer | 183 | 59196.1 | 1 | GenBank (10528) | Trypanosoma brucei brucei | |
| 44 | RA (BH) | SrRNA-4 | polymer | 136 | 43694.8 | 1 | GenBank (10519) | Trypanosoma brucei brucei | |
| 45 | SA (BI) | 60S ribosomal protein L18 | polymer | 193 | 21929.2 | 1 | UniProt (P50885) Pfam (PF17135) | Trypanosoma brucei brucei | |
| 46 | TA (BK) | 60S ribosomal protein L10, putative | polymer | 213 | 24785.3 | 1 | UniProt (Q38EC5) Pfam (PF00252) | Trypanosoma brucei brucei | |
| 47 | UA (BL) | 60S ribosomal protein L11, putative | polymer | 194 | 22420.4 | 1 | UniProt (Q38EI9) Pfam (PF00281) Pfam (PF00673) | Trypanosoma brucei brucei | |
| 48 | VA (BN) | 60S ribosomal protein L13 | polymer | 218 | 25492.0 | 1 | UniProt (Q57V55) Pfam (PF01294) | Trypanosoma brucei brucei | |
| 49 | WA (BO) | 60S ribosomal protein L13a, putative | polymer | 222 | 25791.8 | 1 | UniProt (Q585J5) Pfam (PF00572) | Trypanosoma brucei brucei | |
| 50 | XA (BP) | 40S ribosomal protein L14, putative | polymer | 189 | 21521.5 | 1 | UniProt (Q383F5) Pfam (PF00467) Pfam (PF01929) | Trypanosoma brucei brucei | |
| 51 | YA (BQ) | Ribosomal protein L15 | polymer | 221 | 26477.0 | 1 | UniProt (Q38CY7) Pfam (PF00827) | Trypanosoma brucei brucei | |
| 52 | ZA (BR) | 60S ribosomal protein L17, putative | polymer | 166 | 19147.7 | 1 | UniProt (Q385T6) Pfam (PF00237) | Trypanosoma brucei brucei | |
| 53 | AB (BS) | 60S ribosomal protein L18a | polymer | 179 | 21008.5 | 1 | UniProt (Q382C4) Pfam (PF01775) | Trypanosoma brucei brucei | |
| 54 | BB (BT) | 60S ribosomal protein L19, putative | polymer | 260 | 29494.1 | 1 | UniProt (Q57ZI7) Pfam (PF01280) Pfam (PF25476) | Trypanosoma brucei brucei | |
| 55 | CB (BU) | 60S ribosomal protein L21E, putative | polymer | 159 | 18072.3 | 1 | UniProt (Q4FKD4) Pfam (PF01157) | Trypanosoma brucei brucei | Ribosomal protein L21E (60S),putative |
| 56 | DB (BV) | 60S ribosomal protein L22, putative | polymer | 130 | 15288.9 | 1 | UniProt (Q383R3) Pfam (PF01776) | Trypanosoma brucei brucei | |
| 57 | EB (BW) | 60S ribosomal protein L23, putative | polymer | 139 | 14989.7 | 1 | UniProt (Q38DP2) Pfam (PF00238) | Trypanosoma brucei brucei | |
| 58 | FB (BX) | 60S ribosomal protein L23a | polymer | 164 | 18211.6 | 1 | UniProt (P41165) | Trypanosoma brucei brucei | L25 |
| 59 | GB (BY) | Ribosomal protein L24 | polymer | 125 | 14633.3 | 1 | UniProt (O77067) | Trypanosoma brucei brucei | |
| 60 | HB (BZ) | 60S ribosomal protein L26, putative | polymer | 143 | 16497.5 | 1 | UniProt (Q38D25) Pfam (PF16906) Pfam (PF00467) | Trypanosoma brucei brucei | |
| 61 | IB (Ba) | 60S ribosomal protein L27 | polymer | 133 | 15618.5 | 1 | UniProt (Q381J6) Pfam (PF00467) Pfam (PF01777) | Trypanosoma brucei brucei | |
| 62 | JB (Bb) | 60S ribosomal protein L27a | polymer | 145 | 16307.2 | 1 | UniProt (Q38DN9) Pfam (PF00828) | Trypanosoma brucei brucei | |
| 63 | KB (Bc) | 60S ribosomal protein L28, putative | polymer | 146 | 16901.0 | 1 | UniProt (Q385E9) Pfam (PF01778) | Trypanosoma brucei brucei | |
| 64 | LB (Bd) | 60S ribosomal protein L29 | polymer | 71 | 8244.6 | 1 | UniProt (Q383S6) Pfam (PF01779) | Trypanosoma brucei brucei | |
| 65 | MB (Be) | 60S ribosomal protein L2, putative | polymer | 260 | 28401.1 | 1 | UniProt (Q57W56) Pfam (PF00181) Pfam (PF03947) | Trypanosoma brucei brucei | |
| 66 | NB (Bf) | Ribosomal protein L3, mitochondrial, putative | polymer | 429 | 48816.0 | 1 | UniProt (Q581Q1) Pfam (PF00297) | Trypanosoma brucei brucei | |
| 67 | OB (Bg) | 60S ribosomal protein L30 | polymer | 105 | 11531.4 | 1 | UniProt (P49153) | Trypanosoma brucei brucei | |
| 68 | PB (Bh) | 60S ribosomal subunit protein L31, putative | polymer | 188 | 21752.9 | 1 | UniProt (Q38DH8) Pfam (PF01198) | Trypanosoma brucei brucei | |
| 69 | QB (Bi) | 60S ribosomal protein L32, putative | polymer | 132 | 15432.2 | 1 | UniProt (Q38CL1) Pfam (PF01655) | Trypanosoma brucei brucei | |
| 70 | RB (Bj) | 60S ribosomal protein L34, putative | polymer | 170 | 19396.3 | 1 | UniProt (Q383V6) Pfam (PF01199) | Trypanosoma brucei brucei | |
| 71 | SB (Bk) | 60S ribosomal protein L35, putative | polymer | 127 | 15187.3 | 1 | UniProt (Q38FW8) Pfam (PF00831) | Trypanosoma brucei brucei | |
| 72 | TB (Bl) | 60S ribosomal protein L35A, putative | polymer | 149 | 17061.0 | 1 | UniProt (Q584G9) Pfam (PF01247) | Trypanosoma brucei brucei | |
| 73 | UB (Bm) | Ribosomal protein L36, putative | polymer | 109 | 12492.0 | 1 | UniProt (Q38CY6) Pfam (PF01158) | Trypanosoma brucei brucei | |
| 74 | VB (Bn) | Ribosomal protein L37 | polymer | 84 | 10128.9 | 1 | UniProt (Q386L1) Pfam (PF01907) | Trypanosoma brucei brucei | |
| 75 | WB (Bo) | 60S ribosomal protein L37a, putative | polymer | 93 | 10482.3 | 1 | UniProt (Q38AW9) Pfam (PF01780) | Trypanosoma brucei brucei | |
| 76 | XB (Bp) | 60S ribosomal protein L38, putative | polymer | 82 | 9527.4 | 1 | UniProt (Q38FV6) Pfam (PF01781) | Trypanosoma brucei brucei | |
| 77 | YB (Bq) | 60S ribosomal protein L39, putative | polymer | 51 | 6568.0 | 1 | UniProt (Q57UJ8) Pfam (PF00832) | Trypanosoma brucei brucei | |
| 78 | ZB (Br) | 60S ribosomal protein L4 | polymer | 374 | 41941.2 | 1 | UniProt (Q582N2) Pfam (PF00573) Pfam (PF14374) | Trypanosoma brucei brucei | |
| 79 | AC (Bs) | Ubiquitin-60S ribosomal protein L40 | polymer | 128 | 14685.3 | 1 | UniProt (P21899) | Trypanosoma brucei brucei | |
| 80 | BC (Bt) | 60S ribosomal protein L44 | polymer | 106 | 12488.8 | 1 | UniProt (P17843) | Trypanosoma brucei brucei | |
| 81 | CC (Bu) | 60S ribosomal protein L5, putative | polymer | 308 | 34710.2 | 1 | UniProt (Q38CY8) Pfam (PF17144) Pfam (PF14204) | Trypanosoma brucei brucei | |
| 82 | DC (Bv) | 60S ribosomal protein L6, putative | polymer | 192 | 21248.0 | 1 | UniProt (Q389K1) Pfam (PF01159) | Trypanosoma brucei brucei | |
| 83 | EC (Bw) | 60S ribosomal protein L7, putative | polymer | 257 | 29416.7 | 1 | UniProt (Q57V35) Pfam (PF08079) Pfam (PF00327) | Trypanosoma brucei brucei | |
| 84 | FC (Bx) | 60S ribosomal protein L7a | polymer | 276 | 30961.6 | 1 | UniProt (Q57VM1) Pfam (PF01248) | Trypanosoma brucei brucei | |
| 85 | GC (By) | 60S ribosomal protein L9, putative | polymer | 189 | 21897.4 | 1 | UniProt (Q38CD0) Pfam (PF00347) | Trypanosoma brucei brucei | |
| 86 | HC (Bz) | 60S ribosomal protein L41 | polymer | 34 | 4348.4 | 1 | UniProt (G0U1J3) | Trypanosoma brucei brucei | |
| 87 | AE, AI, AJ, AK, AN... (AA, BA, BB, BE, BR...) | MAGNESIUM ION | non-polymer | 24.3 | 224 | Chemie (MG) PubChem (888) | |||
| 88 | AG, AL, AR, BG, BL... (BA, BQ, BE, AA, BG...) | SPERMIDINE | non-polymer | 145.2 | 62 | Chemie (SPD) PubChem (1102) | |||
| 89 | KC, KF, KR, LR, MR... (A9, AV, Bn, Bo, Bs...) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) PubChem (32051) | |||
| 90 | CF, EF, OC (AA) | GENETICIN | non-polymer | 496.6 | 3 | Chemie (GET) PubChem (123865) | |||
| 91 | DG, FG, FL, HL, LL... (BA, BB, AA) | 1,4-DIAMINOBUTANE | non-polymer | 88.2 | 14 | Chemie (PUT) PubChem (1045) | |||
| 92 | TC (AA) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 93 | AD, AH, AM, BD, BH... (AA, BA, BB, BF, Bb...) | POTASSIUM ION | non-polymer | 39.1 | 69 | Chemie (K) PubChem (813) | |||
| 94 | AF, BF, BP, CP, DP... (AA, BB, Be, BA) | SODIUM ION | non-polymer | 23.0 | 17 | Chemie (NA) PubChem (923) | |||
| 95 | AS, AT, BS, BT, CS... (BD, Bo, BE, Bq, BF...) | water | water | 18.0 | 2748 | Chemie (HOH) |
Sequence modifications
A8: 1 - 57 (UniProt: G0UD55)
AH: 1 - 144 (UniProt: P19800)
| PDB | External Database | Details |
|---|---|---|
| His 5 | Asp 5 | conflict |
| Ser 19 | Ala 19 | conflict |
| Asn 50 | His 50 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ias 131 | Asp 131 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 86 |
| Total formula weight | 3663097.5 | |
| Non-Polymers* | Number of molecules | 396 |
| Total formula weight | 21177.6 | |
| All* | Total formula weight | 3684275.0 |
