9SPQ
p53 cancer mutant V272M in complex with DARPin C10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cellular tumor antigen p53 | polymer | 202 | 22753.8 | 1 | UniProt (P04637) Pfam (PF00870) | Homo sapiens (human) | Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53 |
| 2 | B (E) | DARPin C10 | polymer | 126 | 13527.3 | 1 | synthetic construct | ||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) | |||
| 4 | D, E (A, E) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | F, G (A, E) | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A: 94 - 294 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| Ser 93 | - | expression tag |
| Met 272 | Val 272 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36281.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 189.5 | |
| All* | Total formula weight | 36470.7 |
