9SPM
p53 cancer mutant V143A in complex with DARPin C10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cellular tumor antigen p53 | polymer | 202 | 22693.7 | 1 | UniProt (P04637) Pfam (PF00870) | Homo sapiens (human) | Antigen NY-CO-13,Phosphoprotein p53,Tumor suppressor p53 |
| 2 | B (E) | DARPin C10 | polymer | 126 | 13527.3 | 1 | synthetic construct | ||
| 3 | C, E, F, G, H... (A, E) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) PubChem (32051) | |||
| 5 | K, L (A, E) | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A: 94 - 294 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| Ser 93 | - | expression tag |
| Ala 143 | Val 143 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36221.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 499.9 | |
| All* | Total formula weight | 36720.9 |
