9SOZ

SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 006

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	2'-O-methyltransferase nsp16	polymer	302	33701.6	1	UniProt (P0DTD1)	Severe acute respiratory syndrome coronavirus 2	Non-structural protein 16,nsp16
2	B (B)	Non-structural protein 10	polymer	142	15078.3	1	UniProt (P0DTC1)	Severe acute respiratory syndrome coronavirus 2	nsp10,Growth factor-like peptide,GFL
3	C (A)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES) PubChem (4478249)
4	D (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL) PubChem (753)
5	E (A)	3-[1-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-1,2,3-triazol-4-yl]propanoic acid	non-polymer		390.4	1	Chemie (A1JPA)
6	F, G (B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN) PubChem (32051)
7	H, I (A, B)	water	water		18.0	190	Chemie (HOH)

Sequence modifications

A: 1 - 298 (UniProt: P0DTD1)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag

B: 1 - 139 (UniProt: P0DTC1)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48779.9
Non-Polymers*	Number of molecules	5
	Total formula weight	808.5
All*	Total formula weight	49588.4

*Water molecules are not included.