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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9SLM

GABA-A a4b3d receptor in complex with GABA and Nb24

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)		Gamma-aminobutyric acid receptor subunit alpha-4,Gamma-aminobutyric acid type A receptor subunit alpha4polymer36441783.32UniProt (Q9D6F4)
UniProt (F6UBA8)		Homo sapiens (human)GABA(A) receptor subunit alpha-4,GABAAR subunit alpha-4
2B, D
(B, D)		Gamma-aminobutyric acid receptor subunit beta-3polymer45151615.12UniProt (P28472)Homo sapiens (human)GABA(A) receptor subunit beta-3,GABAAR subunit beta-3
3E
(E)		Gamma-aminobutyric acid receptor subunit deltapolymer43048234.01UniProt (O14764)Homo sapiens (human)GABA(A) receptor subunit delta,GABAAR subunit delta
4F, G
(F, G)		Nanobody Nb24polymer12313433.82Lama glama
5H
(O)		beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched383.31In PDB
GlyTouCan (G90333CG)
6I
(P)		beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.51In PDB
GlyTouCan (G44266EX)
7J, K, P, Q, R...
(A, B, C, D, E)		2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.28Chemie (NAG)
PubChem (24139)
8L, N, S, W
(A, B, D)		DECANEnon-polymer142.34Chemie (D10)
PubChem (15600)
9M
(A)		1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATEnon-polymer647.91Chemie (PX6)
10O, U
(B, D)		GAMMA-AMINO-BUTANOIC ACIDnon-polymer103.12Chemie (ABU)
PubChem (119)
11Y, Z
(A, C)		waterwater18.02Chemie (HOH)
Sequence modifications
A, C: 2 - 308 (UniProt: Q9D6F4)
PDBExternal DatabaseDetails
Gly 1-expression tag
Thr 120Met 155engineered mutation
Thr 309-linker
Asn 310-linker
Ser 311-linker
Gln 312-linker
Pro 313-linker
Ala 314-linker
Arg 315-linker
Ala 316-linker
Ala 317-linker
A, C: 390 - 427 (UniProt: F6UBA8)
PDBExternal DatabaseDetails
Gly 428-expression tag
Thr 429-expression tag
Lys 430-expression tag
His 431-expression tag
His 432-expression tag
His 433-expression tag
His 434-expression tag
His 435-expression tag
His 436-expression tag
B, D: 7 - 307 (UniProt: P28472)
PDBExternal DatabaseDetails
Gln 1-expression tag
Ser 2-expression tag
Val 3-expression tag
Asn 4-expression tag
Asp 5-expression tag
Pro 6-expression tag
Val 302Val 327linker
Asn 303Asn 328linker
Tyr 304Tyr 329linker
Ile 305Ile 330linker
Phe 306Phe 331linker
Phe 307Phe 332linker
B, D: 422 - 448 (UniProt: P28472)
PDBExternal DatabaseDetails
Ser 307-linker
Gln 307-linker
Pro 307-linker
Ala 307-linker
Gly 307-linker
Thr 307-linker
Ala 307-linker
Asp 307-linker
Leu 307-linker
Glu 307-linker
Asp 307-linker
Asn 307-linker
Trp 307-linker
Glu 307-linker
Thr 307-linker
Leu 307-linker
Asn 307-linker
Asp 307-linker
Asn 307-linker
Leu 307-linker
Lys 307-linker
Val 307-linker
Ile 307-linker
Glu 307-linker
Lys 307-linker
Ala 307-linker
Asp 308-linker
Asn 308-linker
Ala 308-linker
Ala 308-linker
Gln 308-linker
Val 308-linker
Lys 308-linker
Asp 308-linker
Ala 308-linker
Leu 308-linker
Thr 308-linker
Lys 308-linker
Met 308-linker
Arg 308-linker
Ala 308-linker
Ala 308-linker
Ala 308-linker
Leu 308-linker
Asp 308-linker
Ala 308-linker
Gln 308-linker
Lys 308-linker
Ala 308-linker
Thr 308-linker
Pro 308-linker
Pro 308-linker
Lys 309-linker
Leu 309-linker
Glu 309-linker
Asp 309-linker
Lys 309-linker
Ser 309-linker
Pro 309-linker
Asp 309-linker
Ser 309-linker
Pro 309-linker
Glu 309-linker
Met 309-linker
Lys 309-linker
Asp 309-linker
Phe 309-linker
Arg 309-linker
His 309-linker
Gly 309-linker
Phe 309-linker
Asp 309-linker
Ile 309-linker
Leu 309-linker
Val 309-linker
Gly 309-linker
Gln 309-linker
Ile 309-linker
Asp 310-linker
Asp 310-linker
Ala 310-linker
Leu 310-linker
Lys 310-linker
Leu 310-linker
Ala 310-linker
Asn 310-linker
Glu 310-linker
Gly 310-linker
Lys 310-linker
Val 310-linker
Lys 310-linker
Glu 310-linker
Ala 310-linker
Gln 310-linker
Ala 310-linker
Ala 310-linker
Ala 310-linker
Glu 310-linker
Gln 310-linker
Leu 310-linker
Lys 310-linker
Thr 310-linker
Thr 310-linker
Arg 310-linker
Asn 311-linker
Ala 311-linker
Tyr 311-linker
Ile 311-linker
Gln 311-linker
Lys 311-linker
Tyr 311-linker
Leu 311-linker
Thr 417-linker
Gly 418-linker
Arg 419-linker
Ala 420-linker
Ala 421-linker
E: 0 - 218 (UniProt: O14764)
PDBExternal DatabaseDetails
Met -83-initiating methionine
Gly -82-expression tag
Ile -81-expression tag
Leu -80-expression tag
Pro -79-expression tag
Ser -78-expression tag
Pro -77-expression tag
Gly -76-expression tag
Met -75-expression tag
Pro -74-expression tag
Ala -73-expression tag
Leu -72-expression tag
Leu -71-expression tag
Ser -70-expression tag
Leu -69-expression tag
Val -68-expression tag
Ser -67-expression tag
Leu -66-expression tag
Leu -65-expression tag
Ser -64-expression tag
Val -63-expression tag
Leu -62-expression tag
Leu -61-expression tag
Met -60-expression tag
Gly -59-expression tag
Cys -58-expression tag
Val -57-expression tag
Ala -56-expression tag
Glu -55-expression tag
Met -54-expression tag
Asp -53-expression tag
Glu -52-expression tag
Lys -51-expression tag
Thr -50-expression tag
Thr -49-expression tag
Gly -48-expression tag
Trp -47-expression tag
Arg -46-expression tag
Gly -45-expression tag
Gly -44-expression tag
His -43-expression tag
Val -42-expression tag
Val -41-expression tag
Glu -40-expression tag
Gly -39-expression tag
Leu -38-expression tag
Ala -37-expression tag
Gly -36-expression tag
Glu -35-expression tag
Leu -34-expression tag
Glu -33-expression tag
Gln -32-expression tag
Leu -31-expression tag
Arg -30-expression tag
Ala -29-expression tag
Arg -28-expression tag
Leu -27-expression tag
Glu -26-expression tag
His -25-expression tag
His -24-expression tag
Pro -23-expression tag
Gln -22-expression tag
Gly -21-expression tag
Gln -20-expression tag
Arg -19-expression tag
Glu -18-expression tag
Pro -17-expression tag
Asp -16-expression tag
Tyr -15-expression tag
Asp -14-expression tag
Ile -13-expression tag
Pro -12-expression tag
Thr -11-expression tag
Thr -10-expression tag
Glu -9-expression tag
Asn -8-expression tag
Leu -7-expression tag
Tyr -6-expression tag
Phe -5-expression tag
Gln -4-expression tag
Gly -3-expression tag
Thr -2-expression tag
Gly -1-expression tag
E: 392 - 418 (UniProt: O14764)
PDBExternal DatabaseDetails
Leu 219-linker
Arg 220-linker
Arg 221-linker
Asn 222-linker
Arg 223-linker
Gly 224-linker
Val 225-linker
Tyr 226-linker
Ile 227-linker
Ile 228-linker
Gln 229-linker
Ser 230-linker
Tyr 231-linker
Met 232-linker
Pro 233-linker
Ser 234-linker
Val 235-linker
Leu 236-linker
Leu 237-linker
Val 238-linker
Ala 239-linker
Met 240-linker
Ser 241-linker
Trp 242-linker
Val 243-linker
Ser 244-linker
Phe 245-linker
Trp 246-linker
Ile 247-linker
Ser 248-linker
Gln 249-linker
Ala 250-linker
Ala 251-linker
Val 252-linker
Pro 253-linker
Ala 254-linker
Arg 255-linker
Val 256-linker
Ser 257-linker
Leu 258-linker
Gly 259-linker
Ile 260-linker
Thr 261-linker
Thr 262-linker
Val 263-linker
Leu 264-linker
Thr 265-linker
Met 266-linker
Thr 267-linker
Thr 268-linker
Leu 269-linker
Met 270-linker
Val 271-linker
Ser 272-linker
Ala 273-linker
Arg 274-linker
Ser 275-linker
Ser 276-linker
Leu 277-linker
Pro 278-linker
Arg 279-linker
Ala 280-linker
Ser 281-linker
Ala 282-linker
Ile 283-linker
Lys 284-linker
Ala 285-linker
Leu 286-linker
Asp 287-linker
Val 288-linker
Tyr 289-linker
Phe 290-linker
Trp 291-linker
Ile 292-linker
Cys 293-linker
Tyr 294-linker
Val 295-linker
Phe 296-linker
Val 297-linker
Phe 298-linker
Ala 299-linker
Ala 300-linker
Leu 301-linker
Val 302-linker
Glu 303-linker
Tyr 304-linker
Ala 305-linker
Phe 306-linker
Ala 307-linker
His 308-linker
Phe 309-linker
Asn 310-linker
Ala 311-linker
Asp 312-linker
Ser 313-linker
Gln 314-linker
Pro 315-linker
Ala 316-linker
Arg 317-linker
Ala 318-linker
Ala 319-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight261898.4
BranchedNumber of molecules2
Total formula weight969.9
Non-Polymers*Number of molecules15
Total formula weight3192.9
All*Total formula weight266061.2
*Water molecules are not included.

259015

PDB entries from 2026-09-02

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