9SGH
Bimekizumab Fab in complex with human interleukin-17A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, H) | Bimekizumab Fab heavy-chain | polymer | 232 | 25006.0 | 2 | Mus musculus | ||
| 2 | B, F (B, L) | Bimekizumab Fab light-chain | polymer | 213 | 23532.1 | 2 | Mus musculus | ||
| 3 | D, E (I, J) | Interleukin-17A | polymer | 122 | 14119.9 | 2 | UniProt (Q16552) Pfam (PF06083) | Homo sapiens (human) | IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8 |
| 4 | G, H, I, J, L... (B, H, I, J) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) PubChem (32051) | |||
| 5 | K (I) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 6 | N, O, P, Q, R... (A, B, H, I, J...) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
I, J: 34 - 155 (UniProt: Q16552)
| PDB | External Database | Details |
|---|---|---|
| Ser 129 | Cys 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 125315.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 487.4 | |
| All* | Total formula weight | 125803.4 |
