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9SDY

Structure of RBR E2 variant binding to CUL5-RBX2 bound ARIH2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(G)
L3A2-1polymer15517854.51synthetic construct
2B
(R)
RING-box protein 2polymer11312697.41UniProt (Q9UBF6)
Pfam (PF12678)
Homo sapiens (human)Rbx2,CKII beta-binding protein 1,CKBBP1,RING finger protein 7,Regulator of cullins 2,Sensitive to apoptosis gene protein
3C
(C)
Cullin-5polymer78091085.31UniProt (Q93034)
Pfam (PF00888)
Pfam (PF10557)
Homo sapiens (human)CUL-5,Vasopressin-activated calcium-mobilizing receptor 1,VACM-1
4D
(H)
E3 ubiquitin-protein ligase ARIH2polymer49357893.81UniProt (O95376)
Pfam (PF00097)
Pfam (PF01485)
Pfam (PF22191)
Pfam (PF19422)
Homo sapiens (human)ARI-2,Protein ariadne-2 homolog,RING-type E3 ubiquitin transferase ARIH2,Triad1 protein
5E, F, G, H, I...
(R, H)
ZINC IONnon-polymer65.47Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight179531.1
Non-Polymers*Number of molecules7
Total formula weight457.9
All*Total formula weight179988.9
*Water molecules are not included.

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PDB entries from 2026-01-14

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