9SCY

The R90H clinical variant of human bisphosphoglycerate mutase (hBPGM)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Bisphosphoglycerate mutase	polymer	267	31099.3	4	UniProt (P07738) Pfam (PF00300)	Homo sapiens (human)	BPGM,2,3-bisphosphoglycerate mutase,erythrocyte,3-bisphosphoglycerate synthase,3-diphosphoglycerate mutase,DPGM,BPG-dependent PGAM
2	E, F, G, J (A, B, C, D)	CITRIC ACID	non-polymer		192.1	4	Chemie (CIT) PubChem (311)
3	H, I (C)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	K, L, M, N (A, B, C, D)	water	water		18.0	362	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 259 (UniProt: P07738)

PDB	External Database	Details
His 90	Arg 90	engineered mutation
Leu 260	-	expression tag
Glu 261	-	expression tag
His 262	-	expression tag
His 263	-	expression tag
His 264	-	expression tag
His 265	-	expression tag
His 266	-	expression tag
His 267	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	124397.3
Non-Polymers*	Number of molecules	6
	Total formula weight	892.6
All*	Total formula weight	125289.9

*Water molecules are not included.