9SAQ
Cryo-EM structure of SARS CoV-2 RdRp S759A mutant in complex with 20-40mer RNA incorporating ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (P) | RNA primer strand (27-MER) | polymer | 27 | 8564.1 | 1 | Severe acute respiratory syndrome coronavirus 2 | ||
| 2 | B (T) | RNA template strand (40-MER) | polymer | 40 | 12720.5 | 1 | Severe acute respiratory syndrome coronavirus 2 | ||
| 3 | C (A) | RNA-directed RNA polymerase nsp12 | polymer | 928 | 106420.6 | 1 | UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680) | Severe acute respiratory syndrome coronavirus 2 | Pol,RdRp,Non-structural protein 12,nsp12 |
| 4 | D (B) | Non-structural protein 8 | polymer | 198 | 21903.0 | 1 | UniProt (P0DTD1) Pfam (PF08717) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 8 |
| 5 | E (C) | Non-structural protein 7 | polymer | 83 | 9248.8 | 1 | UniProt (P0DTD1) Pfam (PF08716) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 7 |
| 6 | F, G (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 5 - 932 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 759 | Ser 5151 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 158857.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 158988.0 |
