9SAN
Crystal structure of SARS-CoV-2 NSP14 in complex with compound 27
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Guanine-N7 methyltransferase nsp14 | polymer | 525 | 59544.2 | 2 | UniProt (P0DTD1) Pfam (PF06471) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN |
| 2 | C, J (A, B) | (2~{R},3~{R},4~{S},5~{S})-2-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)-5-(1,3-benzothiazol-2-ylsulfanylmethyl)oxolane-3,4-diol | non-polymer | 415.5 | 2 | Chemie (A1JM2) | |||
| 3 | D (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 4 | E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | F, G, H, I, K... (A, B) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 525 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 90 | Asp 6015 | conflict |
| Ala 92 | Glu 6017 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119088.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1420.0 | |
| All* | Total formula weight | 120508.3 |
